The drug Actovegin is an effective medicine that helps speed up the metabolic and recovery processes in the body, as well as improve cell nutrition. It is derived from the blood of calves (hemoderivat), obtained by dialysis.
Treatment with this drug improves blood circulation, helps oxygen and glucose to penetrate into damaged tissues faster. The drug is well tolerated by patients, has no serious consequences and is used in many popular diseases, such as vascular disorders.
There are several forms of release of this tool: solutions for injection, ointment, cream and gels. The most popular among patients are tablets.
The composition and description of the tablets
Tablets contain the main (active) substance, as well as a number of auxiliary components.
The composition of the tablets Actovegin:
| Active substance | Auxiliary substance | Shell composition |
|---|---|---|
| deproteinized hemoderivate - 200 mg. | povidone, talc, stearic acid cellulose.
| wax, acacia gum, quinoline dye, phthalate, diethyl phthalate, macrogol, aluminum, talc, sucrose, titanium dioxide and povidone. |
The tablets have a round shape and a glossy green-yellow coating. The medicine is packaged in glass bottles in a protective cardboard box. Each bottle of 50 tablets.
pharmachologic effect
Aktovegin pharmacological group - antihypoxants and antioxidants. The drug restores and stimulates metabolic processes in the circulatory system, helps transport glucose and oxygen to the body.
During therapy with pills, cells absorb nutrients more quickly, their membrane is normalized, and lactate synthesis is reduced.
Other pharmacological properties of tablets:
- cell supply with adenosine diphosphate, adenosine triphosphate and phosphocreatine;
- increased concentrations of aspartate, glutamate and gamma-aminobutyric acid;
- removal of burning sensation, pain, numbness of the extremities;
- stabilization of the mental state;
- improves brain function;
- activation of the processes of regeneration of damaged tissues;
- stimulation of reparative processes.
Most often, Actovegin is used in the fight against diabetic polyneuropathy of the extremities. The drug helps to saturate the cells with oxygen, assimilate and dispose of it. This process, similar to insulin-like, stimulates the transportation and oxidation of glucose in the blood.
Indications for use
Actovegin has been used in medical practice for more than 30 years. Its effectiveness is due to evidence-based medicine and numerous studies.
In the complex therapy, tablets are used to treat a wide range of diseases. Especially effective drug in the fight against neuralgic, mental and psychological disorders. Medication is also prescribed to prevent the symptoms of diabetes mellitus and its consequences.
Actovegin tablets are recommended for the following violations:
- problems of metabolism and nutrition of cells;
- vascular diseases of the brain;
- myocardial infarction and its consequences;
- violation of the blood supply to the brain;
- preventing varicose veins;
- diabetes mellitus, its effects and pre diabetic condition;
- poorly healed wounds, calluses, burns, pressure sores and other damage to the epidermis.
Most effective Actovegin has in the treatment of neurological diseases: stress, depression, neurosis, encephalopathy, traumatic brain injury, age-related dementia, inadequate nutrition of the brain, cerebrovascular disease.
Contraindications
Actovegin is considered a safe drug that is prescribed even to infants. It has no serious contraindications and side effects. However, there are a number of cases when pills are contraindicated.
You can not take the drug in the following cases:
- renal failure;
- violation of urine outflow;
- heart failure II or III;
- with pulmonary edema.
Also, the drug is prohibited for women during lactation, and during pregnancy only by special instructions of the doctor.
Dosage and administration
The drug is prescribed only by doctor's prescription and is issued from pharmacies strictly by prescription.
The instructions for use for tablets Actovegin contains the following information:
| Patient category | Dosage | Reception ratio |
|---|---|---|
| Children from 3 to 12 years | 1/4 - 1/2 tablets | 2-3 times a day |
| Adults | 1-2 pieces | 3 times a day |
| Patients with diabetic polyneuropathy | 2-3 pieces | 3 times a day |
| Babies | Only as directed by a doctor |
The drug must be taken 30 minutes before a meal, swallowing the pill whole and washing it down with clean water. Chewing or crushing tablets is not recommended. To achieve the desired effect, the drug is taken from 4 to 6 weeks. With diabetes - from 4 to 6 months.
How to take pills for children?
Actovegin is a safe drug, but it is not recommended to give it to children under 3 years old, this is indicated in the instructions in the contraindications section. However, in medical practice, this drug is often prescribed to newborns to prevent certain diseases associated with disorders in the brain.
In which case the drug is administered to infants:
- cerebral hypoxia;
- entanglement of the baby with the umbilical cord;
- brain injuries during childbirth and during pregnancy;
- blood supply problems in the brain.
As a rule, children under 3 years old are prescribed injections of 0.4 mg per 1 kg of body weight once a day. After 3 years, children can take half-pills 2-3 times a day, previously dissolved in water.
Instructions for use during pregnancy and lactation
Actovegin tablets during pregnancy are not contraindicated, however, are prescribed with caution and only on the advice of a doctor.
The indications for taking the drug during pregnancy are:
- fetal hypoxia;
- slow growth of the fetus;
- fetal brain injury.
During breastfeeding, it is better to refuse from taking the drug, so as not to provoke an allergic reaction in the newborn.
Overdose and side effects
A side effect of the pills can be an allergic reaction to one or more components of the drug. If the patient showed signs of allergy: urticaria, itching, burning, tearing - it is necessary to stop taking the drug and pick up an analogue.
In the event of an overdose of the drug, you should carefully consider your well-being, if the health has worsened - immediately seek medical help.
Drug interactions and special instructions
Actovegin tablets interact well with other drugs, they are often prescribed in complex therapy with many drugs.
The drug is strictly forbidden to take with alcohol.
It should be borne in mind that Actovegin has a shelf life of 3 years, after which time pills are prohibited.
Price in Russia and Ukraine
The average cost of Actovegin tablets in Russia - 1500 rubles.
The average cost of Actovegin tablets in Ukraine - 650 UAH.
Analogs of the drug
Actovegin is a foreign drug produced in Switzerland by the popular company Nycomed, which manufactures drugs together with Japan. The price category of Actovegin is considered high, however, in the pharmacological market there are cheaper similar drugs, including domestic production.
Actovegin substitutes include:
- Noben - 500 rubles / 250 UAH.
- Divaz - 300 rubles. / 130 UAH.
- Mexidol - 400 rubles / 170 UAH.
- Omaron - 200 rubles / 90 UAH.
The most similar analogue of Actovegin in its composition and pharmaceutical properties is considered the drug Solcoseryl, which is also produced in Switzerland, but has a shorter shelf life. The price of these tablets in Russia is about 900 rubles, in Ukraine - 200 UAH.
Tablet reviews
The long-term effective practice of using Actovegin has been proved by numerous reviews from both the patients themselves and professional doctors.
My one-year-old child was diagnosed with the development of intracranial pressure and hypoxia of the brain. In half a year he threw back his head and had an even spring, he was lagging behind in development. The pediatrician prescribed a complex therapy for us, where Actovegin was the main drug. We drank it for almost a month, then took a break and drank another 2 weeks. At the next admission, the survey did not reveal any abnormalities, oxygen began to flow well into the baby’s brain.
Christina Vdovina, 36 years old, Moscow
I am a professional tourist and I often have injuries, burns, blisters and other, quite serious damage to the skin. In some climatic zones, for example, in the mountains, sores can not pass for months, fester and inflame. The doctor advised to take Actovegin, so that the healing process proceeded quickly and without consequences. The drug helps well, at the cellular level, all injuries pass quickly.
Igor Spiridonov, 29 years old, Kaliningrad
Conclusion
Actovegin is a popular remedy in the fight against many problems of blood supply to the brain, vascular disorders and neurotic disorders.
The price of the drug is high, but there are no 100% analogues in the tablets, so Actovegin is often purchased in Russian and Ukrainian pharmacies.
Drug therapy is carried out not more than a month, and the method of application is not difficult.
A large number of positive feedback from recovered patients indicates the effectiveness of this drug.
Additional information about the drug Actovegin can be found in the following video.
