Anti-inflammatory analgesics sometimes have to take long courses, so doctors advise you to choose the safest and most effective means. The group of such drugs includes Nise. Before using it, it is important to carefully read the instructions.
The composition and effect of Knight
The active ingredient is nimesulide in the amount of 100 mg in each pill. This is a chemical compound of the sulfonamide group. It suppresses the production of enzymes involved in the synthesis of mediators of edema, pain, inflammation. There are also a number of auxiliary components, which include:
- calcium phosphate;
- corn starch;
- Type 114 microcrystalline cellulose;
- carboxymethyl starch sodium;
- magnesium stearate;
- colloidal silicon dioxide;
- purified talc.
This drug is prescribed only to relieve symptoms - it is not used as a therapeutic drug.
Indications for use:
toothache and headache;- pain in the postoperative period;
- arthralgia;
- bursitis;
- post-traumatic pain;
- inflammation of the soft tissues, tendons and ligaments;
- myalgia of rheumatic and other origin;
- febrile syndrome;
- neuralgia
toothache and headache;In addition, Nise, which contains nimesulide, prevents cartilage damage, helps to stop the destruction of collagen. Due to this, it is prescribed for various pathologies of the musculoskeletal system:
- articular syndrome during gouty exacerbations;
- rheumatoid and psoriatic arthritis;
- osteochondrosis;
- ankylosing spondylitis;
- radicular syndrome;
- osteoarthritis;
- tendovaginitis;
- ankylosing spondylitis;
- vertebral pain on the background of scoliosis and other diseases;
- osteoarthritis;
- tendonitis;
- radiculitis;
- pain in osteoporosis.
Instructions for use
This drug acts very quickly, but it is very important to carefully follow the instructions for its use and listen to the recommendations of the attending physician. An overdose of Naiza may cause serious side effects. It is also very important to strictly observe the duration of the treatment course.
This drug is most often prescribed to adults and adolescents over 12 years old with a body weight of more than 40 kg. The standard dosage of the drug is 100 mg.
Children up to 3 years of the drug is not prescribed. If the child has reached the specified age, you can use tablets that are soluble in water. They are available with a dosage of the active ingredient 50 mg.
For toothache
This drug is used to relieve toothache before or after a visit to the dentist. Take it according to the scheme: 1 tablet (100 mg) twice a day. The maximum dosage should not exceed 200 mg per day.
It is advised to drink pills before eating, but if you have any unpleasant sensations in the stomach or intestines, it is better to use Nise tablets after meals. The duration of therapy may not exceed two weeks.
With osteochondrosis
Nise effectively relieves swelling, back pain in osteochondrosis. Take 1 tablet twice a day. According to a similar scheme, they take medicine for other diseases of the musculoskeletal system, which are accompanied by pain.
With headache
It is worth noting that Nise is often drunk with a headache. However, this medicine does not always help. It is recommended to take it if the pain is accompanied by:
- increased body temperature;
- inflammatory processes, such as meningitis;
- voltage;
- overwork;
- stress;
- lack of sleep;
- changing weather conditions;
- osteochondrosis;
- infringement of the nerve roots.
In addition, these medications are not effective if migraine is the cause of the headache. In this case, no anti-inflammatory nonsteroidal medications will help.
For migraine attacks, it is better to take drugs that have a direct effect directly on the dilated blood vessels in the brain and block the sensitivity of the trigeminal nerve receptors, such as triptans.
How long does the medicine last?
The duration of action depends on the cause, the nature of the pain, the intensity of the discomfort. So, 1 tablet of the drug helps to block discomfort for about 10-12 hours. The degree of relief of pain syndrome gradually decreases, because nimesulide begins to be eliminated from the body after 2-5 hours. The maximum analgesic effect is observed 20-25 minutes after taking the pill.
The duration of therapy depends on the situation. Only a doctor can indicate how long you can take pills. The maximum duration of treatment is two weeks.
The maximum duration of symptomatic therapy is 15 days. More often, nimesulide is used until the swelling and signs of inflammation disappear - 7-10 days or less. For headaches, menstrual pains, toothaches, the drug is applied for 2-3 days or once.
Simultaneous intake with alcohol - is it possible?
At the moment, there are no instructions on the simultaneous reception of Niiz and alcoholic beverages. Moreover, the pill can relieve hangover, relieve the condition.
Nevertheless, it is not recommended to combine tablets with alcohol, since ethanol is able to trap fluid in the body, and with it nimesulide, which can provoke dangerous consequences.
Side effects of taking
Submitted pharmacological agent is rarely accompanied by negative concomitant phenomena. More often, tablets are well tolerated, but about 5% of patients are looking for other medicines, as Nise has the following side effects:
dizziness;- nervousness;
- nightmares;
- drowsiness;
- encephalopathy in the form of Reis syndrome;
- headache;
- immune hypersensitivity reactions;
- skin rash (urticaria, eczema, dermatitis);
- anaphylactic shock;
- itching;
- dysuria;
- delayed urine excretion;
- hematuria;
- renal failure;
- interstitial nephritis;
- pronounced swelling of the limbs;
- gastritis;
- flatulence;
- diarrhea;
- stomatitis;
- epigastric pain;
- internal bleeding;
- cholestasis;
- medical jaundice;
- anemia;
- shortness of breath;
- hypertension;
- tides;
- general weakness, decreased performance;
- sharp decrease in body temperature.
dizziness;With special care, you need to take a Nise in the presence of the following problems and diseases:
- disorders of the kidneys and bladder;
- eye disease;
- high blood pressure;
- cardiovascular diseases;
- severe liver damage.
Nimesulide can react with other nonsteroidal anti-inflammatory drugs, so using Naise and similar analgesics at the same time can lead to unwanted side effects.
Contraindications
In the following cases, you cannot take Nise:
- with recurrent polyposis of the nose, paranasal sinuses;
- with bronchial asthma;
- with intolerance to acetylsalicylic acid;
- with hypersensitivity to nimesulide;
- for bleeding: intestinal, gastric, etc .;
- Crohn's disease;
- during the period of acute ulcerative colitis;
- with decompensated heart failure;
- with ulcerative lesions of the gastric mucosa, intestines;
- with hemophilia and other blood diseases;
- with alcoholism;
- with severe renal failure.
These drugs are also not prescribed during pregnancy, lactation, children up to three years.
Nise or Diclofenac - which is better to choose?
It is impossible to say which of these products is better, because each of them has its own scope of application, and the main component is different. So, for example, Diclofenac allows you to remove inflammation in the body, and Nise is more aimed at "eliminating" the consequences.
But the main differences are as follows:
- Diclofenac is contraindicated in people with a history of stomach and intestinal diseases. In such cases, it is better to take nise.
- Nise can not be prescribed to children under 12 years, but Diclofenac in the form of ointment is allowed to use from 6 years. Its reception is carried out strictly under the supervision of a physician. Small dosages are selected, but they also help in the treatment of complex pathologies.
- Nimesulide leads to the suppression of female fertility, which can adversely affect the ability to conceive a child. Diclofenac has no such features.
- Diclofenac has a pronounced analgesic effect. If you need to eliminate one-time the intense pain that provokes an inflamed joint, it is better to choose it. If you need a long-term treatment of diseases of the musculoskeletal system, gel Nise is more suitable.
Diclofenac is available in different forms: there are tablets, suppositories, ointment, gel, solution for intramuscular injections, as well as drops, which are widely used in ophthalmology. Nise is available in three forms: in tablet form, in the form of a gel, in granules for suspension. These preparations have similar indications, however, before taking any medication, you should definitely consult with a specialist and read the instructions.
