Tablets Grandaksin: indications for use, dosage, reviews

Grandaxine refers to tranquilizers. It eliminates fear, anxiety, nervous overstrain.

It does not cause drowsiness and excessive slackness, unlike other similar drugs. Therefore, it can even be used during the day. The tool is not addictive and quickly leaves the body.

Composition and pharmacological action

The main active component of the agent is tofizopam. A certain amount of stearic acid, magnesium stearate, gelatin, potato starch, lactose, monohydrate and other auxiliary components were added to it.

The drug is produced in the form of tablets and has an anxiolytic effect. It affects the body in this way:

1. Eliminates various autonomic disorders.
2. Indicates a moderate stimulating effect.
3. Relieves anxiety, fear, soothes the nervous system.

The tool has no sedative, muscle relaxant and anticonvulsant properties. This is a daily anxiolytic. Because of this, it is suitable for people with a diagnosis of myopathy and myasthenia gravis.

The drug belongs to the group of benzoadepine derivatives, but, unlike other similar drugs, there is no physical and mental dependence when it is used.

After consumption, the tablets are rapidly absorbed in the stomach and intestines. The maximum concentration in the blood is reached within a few hours after ingestion. Most of the substance is excreted in the urine, and the rest in the feces. Fully remedy comes out of the body within eight hours.

Indications for use Grandaksina

Use the drug is necessary to eliminate:

• neurosis and neurosis-like states in which emotional stress arises, autonomic disorders, apathy, moderate anxiety, obsessive experiences;
• reactive depression with moderate and severe symptoms;
• post-traumatic stress disorder;
• climacteric syndrome. In this case, it can be used as an independent tool or in combination with other drugs;
• premenstrual syndrome;
• cardialgia, as an independent means or in combination with other drugs;
• alcohol withdrawal syndrome;
• secondary neurotic symptoms in the form of muscular atrophy, myopathy, if muscle relaxants are contraindicated.

Prescribe the drug should only specialist, as it has a pronounced effect on the nervous system.

Instructions for use of medication

The drug can not cause addiction in humans. If you stop taking it, the withdrawal will not occur. There are no restrictions on its use, as it does not affect the reaction rate and ability to concentrate. In the course of treatment it is necessary to adhere to such recommendations:

1. The effect of the drug does not depend on food intake. Therefore, it can be taken both before and after meals;
2. So that the drug does not cause difficulties in falling asleep, it is not advisable to take it after 16 hours.
3. The dosage should be selected depending on the general condition of the patient, the type and severity of the development of his disease and the individual tolerance of the active substance;
4. Most patients are prescribed about 100 mg per day for 1-2 doses;
5. The body should not receive more than 300 mg of substance per day;
6. Older people and those suffering from renal failure should be given a dose of 2 times less than other patients;
7. The duration of the course of treatment is determined by the attending physician;
8. People with withdrawal syndrome and a high risk of delirium tremens should not take the drug for more than 6 weeks.

Use during pregnancy and lactation

Therefore, during pregnancy there are such features of the appointment:

1. In the first trimester to use the drug is strictly contraindicated, since it can affect the growth and development of the fetus;
2. The last months of pregnancy are also an unsafe period for treatment with Grandaxin. It is possible to appoint means only in special cases.

Substances of the drug have the property to penetrate into breast milk, so during this period, to use tablets Grandaxin is not recommended.

Women during pregnancy and breastfeeding should always consult a specialist before using any drug.

Contraindications and possible adverse reactions

The use of Grandaxine is contraindicated in:

• individual intolerance of individual components of the tool;
• neurotic states accompanied by increased aggressiveness;
• deep depression or excessive excitability;
• first trimester pregnancy;
• breastfeeding;
• a history of apnea;
• congenital lactase deficiency;
• cephalosporins treatment;
• lack of absorption of lactose or glucose in the intestine.

If a person suffers from vascular atherosclerosis, seizures of epilepsy, organic lesions of the brain, acute-angle glaucoma, and acute respiratory failure, then medication should be taken only under the supervision of a physician.

The drug can cause adverse reactions. Among them:

1. Disorders of the central nervous system, which loosen in the form of headaches, sleep disorders, increase in nervous excitability, irritability. A person may suffer from confusion;
2. Increased seizures in people with epilepsy;
3. Disruption of the digestive system, manifested by a deterioration of appetite, dry mouth, flatulence, constipation;
4. Impaired respiratory function;
5. Painful sensations in the muscles, tension of various muscle groups;
6. Allergy. Her symptoms are rash and itching of the skin.

In case of overdose, you must immediately contact the medical institution.

Intake of large doses of the drug leads to nausea and vomiting, confusion, respiratory depression, seizures, coma.

If an overdose occurs, you should immediately call an ambulance and try to induce vomiting. This will prevent the absorption of the substance into the gastrointestinal tract. You can also take activated charcoal or a laxative.

Special instructions and interaction with other medicines

In the process of treatment with Grandaxin, it is necessary to take into account the peculiarities of its interaction with other medicines:

• the active substance of the drug is absorbed faster if taken along with metoclopramide, so the drug will act faster:
• If you simultaneously take Grandaxine with cyclosporins, the concentration of the latter in the blood increases, so they are not recommended to be administered together;
• under the influence of the drug, painkillers, antidepressants, general anesthesia, hypnotics, antipsychotics and sedatives act faster;
• the effect of barbiturates, nicotine, antiepileptic drugs and alcohol leads to a decrease in blood concentrations and a decrease in the effectiveness of Grandaxine;
• co-use with antifungal agents leads to an increase in the amount of the active component in the blood;
• therapeutic effect of the drug is enhanced under the influence of calcium channel blockers;
• Grandaxin reduces the effectiveness of anticoagulants;
• antacids slow down the absorption of the drug;
• oral contraceptives lead to a decrease in the intensity of Grandaxin transformation.

The drug can be purchased at pharmacies. Terms of sale in different countries differ. In Russia, you cannot buy medicine without a prescription. You also need to remember about these features:

1. If a patient has a mental retardation, the age is over 65, if there is kidney and liver disease, then the risk of adverse reactions increases significantly;
2. In case of phobias and obsessive-compulsive disorder, it is better to refuse medication, since the risk of attempts to suicide may increase and aggression will increase;
3. The drug is not recommended to use as an independent means to eliminate depression;
4. In the presence of organic brain lesions and depersonalization, special care must be taken;
5. Each tablet contains 92 mg of lactose, so people who are allergic to this substance should take this fact into account.

Before using the medication, carefully study the instructions.

Cost and analogues of the drug

The cost of the drug in different pharmacies may vary. Depending on the number of tablets in the package, the price of the medicinal product will vary in the range of 300-700 rubles.

This drug, like the others, has analogues. Similar in composition to Grandaxine is the drug Tofizopam. Gidazepam, Tazepam, Afobazol, Neurol have a similar effect on the body.

Reviews

According to reviews, the drug is well tolerated by most people. Grandaxine helps well in the absence of the effect of valerian and sedatives. Improvement of the condition can be noticed within a few days after the start of treatment. Some patients initially noted nausea, but this symptom soon passes.

Conclusion

1. The main active ingredient of the drug is tofizopam. It helps to eliminate vegetative disorders;
2. The drug is prescribed for neurosis, depression, stress disorders;
3. The average dosage per day is 100 mg;
4. In the first trimester of pregnancy and during breastfeeding can not use the drug;
5. In the process of treatment must take into account contraindications. In case of an overdose, an ambulance is urgently needed;
6. Grandaxine cannot be used with certain medications;
7. The average cost of funds - from 300 rubles;
8. Most consumers say the drug is highly effective.

Additional information about Grandaxine can be found in the following video.

Watch the video: Doctor's review of Grandaxin Tofisopam, Emandaxin (May 2024).