Diazolin belongs to the first generation of antihistamines. Despite the fact that drugs of the second and even third generation appeared in pharmacies, this tool has not lost its relevance today.
Characteristics of the drug
Antihistamines - drugs that can block the action of histamine. Histamine is an active biological substance that is produced in the human body. Its maximum concentration is observed during allergic reactions. There are characteristic symptoms of allergy.
Antihistamines are aimed at preventing the development of allergic manifestations.
A distinctive feature of Diazolin is its ability to penetrate the blood-brain barrier, that is, the obstacle between the circulatory system and the brain.
Due to this, after taking the remedy, a slight sedative effect is observed, which often allows using the remedy in the treatment of patients with impaired CNS. Diazolin also reduces swelling of the mucous membranes, relaxes the smooth muscles of the bronchi, uterus, prevents excessive reduction of pressure, reduces the permeability of the walls of blood vessels, eliminates redness on the skin.
Due to the fact that Diazolin can affect other types of receptors, it also has an antipruritic and analgesic effect. The first effect after taking can be noticed after half an hour, and the therapeutic maximum occurs after three to four hours, so that Diazolin can be taken 2-3 times a day. Excreted through the kidneys.
Release form and indications for use
Diazolin is available in tablets and dragees of 0.05 g and 0.1 g. Dosage of 0.05 g is “childish”, 0.1 g is “adult.”
Available tool:
- in packs of 10 or 20 pieces;
- in glass jars of 25 or 20 pieces.
Diazolin is usually used to treat or prevent the development of allergic reactions. It is most effective when:
- hay fever;
- allergic rhinitis;
- hives;
- drug allergies;
- contact dermatitis with severe itching;
- skin reactions after an insect bite;
- Quincke edema.
And although the drug is tolerated by patients quite simply, the likelihood of side effects still remains. In this regard, Diazolin is practically not used for the treatment of chronic allergic diseases. Its main purpose is the relief of symptoms of acute allergic inflammation in the early stages.
Contraindications
This remedy is contraindicated in the following cases:
- astheno-depressive syndrome;
- epilepsy;
- diseases of the cardiovascular system;
- intestinal or bladder atony;
- prostatic hypertrophy;
- angle-closure glaucoma.
Because of the irritating effect on the mucous membrane, Diazolin is not prescribed in the presence of ulcerative processes in the stomach or duodenum, with inflammation of the intestinal walls. It is also prohibited for people who have glucose intolerance, lactose, are hypersensitive to the main active ingredient.
Side effect of medication
Diazolin several times enhances the effect of tranquilizing drugs, analgesics. Therefore, when they are taken at the same time, drowsiness, dizziness, and weakness may appear. However, the opposite effects may also develop: euphoria, sleep problems, headache.
Similar conditions can occur when taking a product with alcoholic beverages. It is required to be cautious to people whose profession is associated with increased concentration of attention, patients with CNS problems.
Among other possible side effects should be indicated:
- dryness of the oral mucosa;
- stomachache;
- heartburn and nausea;
- impaired urination;
- drowsiness;
- anxiety;
- change in skin sensitivity.
In the presence of a pathology of the liver or kidneys, the toxic effect of the drug may be manifested, it is expressed by an increase in side effects. In this case, you must immediately contact a doctor who can prescribe a different drug.
Diazolin Dosage
Depending on the severity of the disease, a single dose of the drug is:
- for adults - 0.5 g;
- 0.01 g - for children.
Diazolin is recommended to be accepted during food or right after meal, without chewing. The tablet or dragee washed down with clean non-carbonated water. The duration of taking the drug varies from 3 to 7 days depending on the nature of the disease and the therapeutic effect.
In connection with the development of drug addiction, the course of treatment is no more than 7-10 days. If a longer treatment is necessary, replace Diazolin with another antihistamine.
During pregnancy
Diazolin crosses the placental barrier. For this reason, it is not recommended to take it during pregnancy, especially in the first three months. In the future, the use of funds in short courses is allowed - no longer than 5 days.
Despite the fact that Diazolin is considered to be a relatively safe medicine, for the entire time of its use, a sufficient amount of data has not been accumulated, according to which one can judge the absolute harmlessness to the fetus. The same applies to the reception during breastfeeding, because the drug penetrates into the milk.
For kids
Children are prescribed a means of pills or tablets of 0.05 g. A single dose is:
- for children aged 3-5 years: 0.05 g to 2 times per day;
- for children 6-10 years: 0.05 to 3 times a day;
- for children 10-12 years old - 0.05 g to 4 times per day.
For children under 3 years old, this remedy can be prescribed only in the case when the therapeutic effect of its administration will prevail over possible side effects. Children under one year means is not prescribed.
The grounds for prescribing children's Diazolin are the same pathologies as in adults. These include:
- allergic dermatosis;
- food or drug allergies;
- fever and so on.
Diazolin is often used by doctors in the treatment of SARS. This is explained by the fact that when a child has a cold, allergens accumulate in the mucous membranes, which can later cause a recurrence of the disease. To prevent allergic reactions from the nasal passages, a prophylactic dose of diazolin is prescribed.
This tool is called one of the most popular, because its cost is 30-50 rubles.
Analogs of the drug: what to replace?
The medicine has no structural analogues. But on the market you can find medicines that have a similar therapeutic effect for allergies.
These remedies include: Loratadin, Ketotifen, Claridol, Tavegil, Suprastin. Active substances in the composition of analogues are categorically incompatible with alcoholic beverages and also have a number of contraindications.
More detailed description:
- Desloratadine. Antiallergic medication blocks H1-receptors. It also has antipruritic and antihistamine effects.
- Ketotifen. The drug, which is widely used as an allergic reaction blocker. Helps stabilize cell membranes, reduces the amount of histamine.
- Claridol An inhibitor that blocks the H1 category of receptors. Taking pills helps stabilize the permeability of blood vessels, has antipruritic and anti-allergic effect.
- Clarosens Another broad-spectrum antihistamine blocker. Helps relieve the course of an allergic reaction, has a slight anesthetic effect.
- Dezal. Antiallergic drug, inhibitor, blocker. Helps prevent the development of an allergic reaction.
- Tavegil. Antiallergic blocker that quickly affects the disease. It has a powerful antipruritic effect.
- Suprastin. Antihistamine blocker broad-spectrum. It has antiemetic and antihistamine properties. Therapeutic activity after administration is maintained for 12 hours.
