Cortexin is a product of domestic production, which is produced by the pharmaceutical company Geropharm. An integral part of this medicinal product are the combined low molecular weight fractions of polypeptides, which are extracted by extracting from the cerebral cortex of cattle and pigs.
This drug helps to improve mental performance and stabilize the central nervous system. In addition, it is widely used for the treatment and prevention of diseases that are directly related to impaired blood circulation in the brain, as well as changes in other cerebral functions.
The composition and release form of the drug
The basis of this drug is a combination of water-soluble polypeptide fractions - Cortexin.
Glycine acts as an excipient, which in this case is a kind of stabilizer.
The drug is available exclusively in the form of a solution for intramuscular injections.
Pharmacology
Cortexin due to neurotransmitters and polypeptides primarily has a tissue-specific effect on the human brain. In addition, he is able to:
Reduce the toxic effects of neurotropic drugs.- Improve learning in children.
- Enhance cognitive abilities.
- Intensify the reparative work of the central nervous system (CNS).
- Quickly restore the functionality of the central nervous system after stressful situations.
Reduce the toxic effects of neurotropic drugs.This nootropic agent helps to balance the number of inhibiting and stimulating amino acids in the brain, and also regulates the level of serotonin and dopamine in the body.
Indications and contraindications
The drug is prescribed to patients for the treatment or prevention of the following ailments:
- violation of hemodynamics in the brain;
- traumatic brain injuries, their consequences;
- encephalopathy of different etiology;
- memory lapses and other cognitive pathologies;
- encephalomyelitis and encephalitis of any degree;
- epileptic syndromes;
- autonomic disorders and asthenic conditions;
- slow speech and psychomotor development in children;
- cerebral palsy in any form.
This drug is strictly contraindicated for women during pregnancy and lactation. Also, do not take patients who have hypersensitivity to the active or auxiliary components of the drug.
Dosage and administration
The drug is used intramuscularly as follows:
- Before the introduction of the content of the ampoule must be diluted in 2 ml of a 0.5% solution of Novocain or in sterile water for injection.
- Foaming should not be allowed when mixing. Therefore, the needle from the syringe must be directed to the wall of the ampoule.
- When the necessary solution is prepared, it is possible to make an injection, following all precautions.
The drug is administered once a day in the following dosage:
- adult patients - 10 ml for ten days;
- children weighing more than twenty kilograms — 10 ml each for ten days;
- children who weigh less than twenty kilograms - 0.5 milligrams per kilogram of weight for five to ten days.
Therapy can be repeated after three to six months.
In the case of acute hemispheric ischemic stroke, as well as during the recovery period, the drug is administered twice a day, ten milligrams per ten days. Repeated therapy is carried out in fifteen days.
Overdose and side effects
Cortexin-based drugs are well tolerated by patients regardless of age. This substance can not cause any side effects. But in rare cases, there may be minor allergic reactions, which are expressed in the appearance of a rash, itching or other skin irritations. Very often, such reactions occur when the drug is diluted with Novocaine.
Therefore, in order to avoid negative reactions Cortexin is recommended to be diluted with sterile water or saline, since these two substances are not capable of causing side effects.
Interaction with other drugs
Since the active substance cortexin does not interact with other drugs, it can be prescribed and taken in combination therapy with any other pharmacological agents.
special instructions
In order for the treatment with this drug to be safe and effective for a person, the following recommendations from specialists should be followed:
Use only as prescribed by the attending physician.- An open bottle of medicine can not be stored for more than one hour. Also, you can not use pre-mixed solution for injection after prolonged storage.
- If necessary, it is allowed to interrupt the therapeutic course for one day. At the same time the next day, the dosage is not necessary to exceed.
- Unused product may be disposed of with other household waste, and no special precautions are required.
Use only as prescribed by the attending physician.The use of Cortexin does not have any effect on the ability to control equipment and mechanisms of increased danger. Also, the drug does not cause drowsiness, irritability and inattention, which allows during its reception to perform any work associated with rapid response.
Cortexin is not addictive. Therefore, its cancellation, like the first method, has no effect on the body.
Similar drugs
The domestic pharmaceutical market is literally overflowing with various Cortexin analogues, which have similar therapeutic characteristics. But at the same time they contain other active components.
The following drugs can be attributed to the analogues of the drug in question:
- Amilonosar, is available in the form of tablets and solution for injection;
- Atsefen, release form - tablets;
- Bravinton, is produced in the form of a concentrate for the subsequent preparation of an infusion solution;
- Vinpotropil, has the form of capsules;
- Vinpocetine, concentrated solution for the preparation of injections;
- Ginkgo biloba, available in tablets and capsules;
- Ginkoum, the manufacturer produces this tool only in capsules;
- Gopantam - tablets;
- Demanol. The release form is a solution that is taken by mouth;
- Glycine. Sublingual or buccal tablets;
- Caviton, is available as a concentrate for injection and in tablets;
- Cogitum, oral solution for internal use;
- Minicem, release form - nasal drops;
- Neupilept, ready solution for intramuscular injections;
- Nooclerin - solution for internal use;
- Nootropil. It is produced in the form of a prepared solution for injection, in capsules and tablets;
- Omaron. Form release - tablets;
- Piracetam. It is produced in the form of a solution for intramuscular injections, tablets, capsules and granules for the preparation of syrup. This drug is widely used due to the syrup, which is well suited for children;
- Semax. It is made in the form of nasal drops;
- Cellex. Intended only for subcutaneous injections;
- Ceraxon. Solutions for internal oral use and intramuscular injections;
- Encephabolum It is made in the form of tablets and suspensions for oral ingestion;
- Epithalamin. It has the form of a powder from which the solution is prepared for intramuscular injections;
- Escotropyl - solution for infusion.
Cost and storage conditions
Average price of Cortexin in pharmacies of the Russian Federation:
- Ten ampoules of five milligrams - 800 rubles.
- Ten ampoules of ten milligrams - 1,100 rubles.
The shelf life of the drug is three years from the date of its production. Storage should be kept out of the reach of children and in a dark place, with an air temperature of no more than twenty-five degrees.
Pharmacies sell freely, without a prescription.
Reviews
A significant proportion of people who took Cortexin speak of it as a drug with a positive effect. In the majority of reviews, it is written that after going through therapy, attention, memory, mental work improved, and tension and nervousness also decreased.
As for negative reviews, there are not so many of them. Most people complain that they did not get any expected effect from the drug, that is, in their opinion, it is a dummy. Some people write about the appearance of allergic reactions with the introduction of this drug.
According to reviews, Cortexin in the treatment of children provided a noticeable effect after the therapeutic course passed. The children began to talk, their speech became more intelligible and fluent, the vocabulary increased markedly. In adolescents, there was an improvement in memory, attention and productivity of thinking. As a result, children perceived new information much faster and more qualitatively. Also, children under five years old have become much better sleep and behave calmer.
By the age of two, my baby said little: something was babbling, but not very active (the birth was rather hard, which, perhaps, had an effect). We went to the neurologist: the song, of course, was long, was observed by the doctors, attended all sorts of courses. I will not speak for long, but only six months later a new doctor prescribed this remedy for us. Not to say that it helped immediately, but by the three years the situation had improved a lot, we were even removed from the register. I do not understand just where we spent half the year before?
Anna, 32 years old
I have a very difficult job in mental terms, I sleep quite a bit and as a result I began to lose activity. Some advised to drink Glycine, but, frankly, did not see any sense in it. My doctor recommended Cortexin to me, although I am terribly afraid of injections. Undoubtedly, it didn’t help me at once, but I began to feel better, more vigorous, I work more and at the same time don’t get so tired.
Anton, 34 years old
Based on the reviews, the therapeutic drug Cortexin can be considered effective for the treatment or prevention of neurological disorders in both adults and children.
