Troxevasin - a drug that is widely used in case of impaired venous circulation. It belongs to the group of angioprotectors.
Description of the dosage form, composition, pharmacological action
The tool comes in the form of cylindrical gelatin capsules. Inside it contains a yellowish powder, lumps are allowed, which are scattered when pressed.
Composition:
| Main component | Additional substances | Capsule |
|---|---|---|
| Troxerutin (0.3 g in 1 capsule) | Magnesium stearate | Gelatin |
| Lactose monohydrate | Titanium dioxide | |
| Benzopyridine |
One blister contains ten capsules, in a carton - five or ten blisters.
The drug has an angioprotective effect, i.e. it affects vessels (mainly veins and capillaries). Troxerutin due to changes in the fibrous layer narrows the pores between the endothelium cells. Slows aggregation and increases the deformation of red blood cells, has anti-inflammatory properties.
In patients with chronic venous insufficiency, the drug relieves swelling, eliminates painful and convulsive syndromes, fights against tissue trophism and varicose ulcers.
By strengthening the walls of blood vessels and reducing their permeability, the development of diabetic retinopathy, a serious complication of diabetes mellitus associated with damage to the retinal vessels, is slowed down. Troxerutin affects the viscosity and fluidity of blood and thereby prevents retinal thrombosis.
Absorption of the active substance after administration is about 15%. The highest concentration in the blood is observed two hours after administration. Therapeutic concentration is kept in the blood for eight hours.
Metabolism of troxerutin occurs in the liver. About 20% of the active substance excreted by the kidneys, about 70% - with bile.
Indications and contraindications
The indications for taking the drug are the following states:
- chronic venous insufficiency;
- postthrombotic syndrome;
- trophic disorders in varicose veins;
- trophic ulcers;
- in the rehabilitation period after vascular sclerotherapy and miniflebectomy (resection of varicose nodules);
- pain, bleeding, itching, exudation with hemorrhoids;
- venous insufficiency, exacerbation of hemorrhoids in pregnant women (from the second trimester);
- as an additional agent for the treatment of diabetic retinopathy, atherosclerotic disease, high blood pressure.
Acceptance of Troxevasin is contraindicated in the following diseases:
- exacerbation of gastric ulcer and 12 duodenal ulcer;
- exacerbation of chronic gastritis;
- individual intolerance to the components of the tool;
- hypersensitivity to routine.
Not recommended long-term use of the drug in patients with renal insufficiency. Treatment in this case should be carried out under close medical supervision.
Instructions for use tablets
The drug Troxevasin is taken orally, strictly during meals. The capsule is swallowed completely with water.
First, one capsule is administered three times a day. Troxerutin has a cumulative effect that develops over the first fourteen days. Further, the course of treatment continues according to the same scheme or decreases to a maintenance dosage (two capsules per day).
After two weeks of treatment, treatment can be suspended, since the effect obtained lasts at least four weeks.
On average, a three- or four-week course is recommended, the further use of the drug is discussed with the physician, taking into account individual characteristics.
Information about the use of the drug in children is not. The effectiveness of treatment increases with simultaneous use of Troxevasin gel, which is applied to the affected area.
Use during pregnancy and lactation
There are no special instructions regarding the use of Troxevazin in pregnancy. The drug can be used according to the standard scheme - a capsule three times a day. The exception is the first trimester - during this period, the agent cannot be taken.
In any case, the advisability of using Troxevasin during pregnancy should be consulted with the gynecologist, who monitors the condition of the woman. For some patients, especially those with complicated pregnancy, the drug may not be suitable.
The question of the possibility of using Troxevazin during breastfeeding needs to be solved again with the doctor, since the drug can penetrate into breast milk in a minimum amount. The decision on the possibility of receiving the funds by the nursing mother is made depending on the prevalence of benefits for the woman over the potential harm to the child.
Side effects, overdose
During the reception may develop side effects:
- from the gastrointestinal tract: epigastric pain, flatulence, diarrhea, heartburn, nausea, erosive lesions of the gastrointestinal tract;
- immune disorders: allergic reactions (rash, pruritus, urticaria, anaphylactic reactions, etc.);
- on the part of the central nervous system: headaches, insomnia, dizziness;
- vascular disorders: ecchymosis (large hemorrhages in the skin or mucous membranes;
- others: flushing of the skin (hot flashes), fatigue.
Dyes that are part of the gelatin capsule can cause allergies, including bronchial asthma.
Side effects disappear after stopping the drug.
Cases of overdose so far not identified. Overdose may cause adverse reactions. In this case, the drug should be stopped immediately. Gastric lavage should be performed and symptomatic therapy should be initiated.
Special instructions and interaction with other medicines
Persons suffering from kidney disease are not recommended long-term administration of troxerutin.
With paresthesia and night tonic convulsions, the remedy should be taken in the morning and at night.
It has been established that the effect of Troxevazin is enhanced when taken together with ascorbic acid. Because of this, in conditions such as influenza, scarlet fever, measles, etc., which are accompanied by increased permeability of the walls of blood vessels, it is advisable to take the drug together with the above acid.
The tool is ineffective for edema of the lower extremities associated with diseases of the cardiovascular system and kidneys. Troxevasin irritates the stomach lining, so it should be drunk only with food.
The presence of lactose in the composition eliminates the possibility of taking in such rare hereditary diseases as lactase deficiency, galactose intolerance or glucose-galactose malabsorption.
The risk of developing allergic reactions is increased in individuals with hypersensitivity to aspirin. Treatment with Troxevasin does not affect the ability to drive vehicles and mechanisms that require high concentration of attention.
Price and analogues
The cost of the drug is about 400 rubles for 50 capsules and 700 rubles for 100.
Among the analogues emit:
- Troxerutin ("Zentiva") - 490-700 rubles for 50-10 capsules;
- Trokserutin Vramed (Sopharma) - 320 rubles for 50 capsules;
- Troxerutin ("Ozone") - 270 rubles for 50 capsules.
Reviews of tablets Troxevasin
According to the manufacturer, the medicine helps with venous insufficiency, hemorrhoidal nodes and even with diabetes mellitus (prevents the occurrence of serious complications). The tool can be used for the prevention of blood clots. I use it to strengthen the veins and prevent varicose veins. To enhance the effect I take along with ascorbic.
There are no specific contraindications for Troxevazin, nor any side effects. According to the instructions, it is enough to drink the capsules for two weeks, which I periodically do. I drink three capsules a day. There will be no pronounced effect immediately, but I can say that at the end of the course, the swelling has gone, and the legs have become much easier.
Inga, 36 years old, St. Petersburg
I was diagnosed with varicose veins of the initial degree. The doctor recommended the use of venotonics. At first I bought Troxevazin gel, but I did not get a pronounced effect.
For better results, I decided to take capsules of the same drug. The effect has become much more noticeable than when using a single gel. I advise you to use these tools in a complex.
Anna, 29 years old, Anapa
Additional information about the drug Troxevasin can be found in the following video.
