The amount of creatinine in the blood indicates the state of the kidneys and is an indicator of the development of the disease. Changes in the concentration of creatinine is realized on the basis of the analysis of venous and capillary blood. The creatinine content in the blood is determined by the amount of unchanged muscle mass of a man.
Creatinine molecule
Creatinine - what is it
Creatinine is a product of the exchange of cells between muscle tissue at the energy level. Its formation occurs as a result of the reaction that occurs when creatine and phosphate collide, begins with muscle contraction and provides additional energy in the human body. In human blood, creatinine level is constant, unchanged value. However, as a result of the disease, the amount of the substance in the blood may vary.
The process of muscle activity requires additional energy, the main reserves of this substance are in the muscle tissue of a person. The contraction of muscle fibers causes the breakdown of creatine phosphate, which proceeds with the release of energy.
After the start of decay, the substance from the myocytes (muscle tissue) is transported by the blood to the kidneys, from where it is removed from the body. The norm of the substance in the body is a stationary and stable indicator, which can still be increased in people whose profession is associated with increased activity.
Normal creatinine level has the following meanings:
- The norm for men is 85-120 µmol / l;
- The norm in the body of women 55 -100 µmol / l;
- In children under 1 year old - 20–40 µmol / l;
- In adolescents after 14 years - 25 - 70 µmol / l.
Fluctuations of the substance indicate a violation of normal physiological processes in the human body, which may be caused by the development of pathology, the formation of a tumor, kidney disease, and hormonal disruptions.
For what purpose and when a blood test is done to determine the level of creatinine in men
The amount of creatinine in the blood of a man indicates the general condition of the muscle tissue and the work of the kidneys.
Deviation from normal indicators indicates a violation in the work of human organs.
An analysis that determines the amount of a substance in the blood is done under the following circumstances:
- A person who is going to become a kidney donor, it is necessary to conduct a thorough examination of the human body;
- There are suspicions regarding the development of kidney disease;
- It is necessary to conduct a study of the level of creatinine in order to identify the possibilities of the organism associated with the removal of toxins
- The manifestation of certain symptoms, indicating the accumulation of residual metabolic products in the blood.
The analysis should be carried out when there is a suspicion of malfunctioning of the kidneys. Violations can be of a different nature, the analysis allows us to more specifically determine what is the root cause of the development of the disease and determines the course of treatment that will be necessary to normalize the condition of the body.
Preparation for the analysis and its conduct
The occurrence of general malaise, back pain, increased pressure can be signs of kidney disease. Correct data obtained from the analysis, are key in determining the disease and the appointment of a course of treatment.
An increase in blood creatinine has the following symptoms:
- Clouding of consciousness;
- Chronic fatigue;
- Labored breathing;
- Severity, slight pain in the lumbar region.
Such symptoms may be short-lived, that is, during a walk, when a person has quickened a step, then a slight dizziness may occur, which will quickly pass, but after a while with increasing load will repeat.
Preparation for the analysis does not require any diets or special diets. Simply follow the following guidelines:
- Within two days before the analysis it is necessary to exclude any physical activity;
- For 24 hours before analysis, refrain from consuming alcoholic beverages, meat, coffee, as well as products with a high content of protein;
- Food should not be consumed for 10–12 hours before a medical test;
- Immediately before the analysis you should sit silently and try to relax;
- The analysis is taken before meals.
Adhering to simple instructions, the analysis will be reliable.
The analysis is carried out on the basis of taken samples of capillary and venous blood, and this is due to the principles and methods of taking the analysis.
Capillary blood is taken from the finger. Venous blood is taken with a syringe from a vein at the crook of the elbow.
How much creatinine should be normal in the blood of an adult male
The amount of creatinine depends on the muscle mass of the person. Changes in muscle tissue are caused by age. There is a table that describes the rate of substance in the blood:
| № | Age | The rate of matter in the blood / µmol / l | The rate of matter in the urine / µmol |
| 1 | 18 - 60 | 87 - 150 | 122 -220 |
| 2 | 60 - 90 | 72 - 144 | 90 - 112 |
| 3 | Over 90 | 61 - 114 | 75 - 111 |
The amount of creatinine in the urine is calculated based on the total weight of the person.
It must be remembered that kidney disease causes various indicators of the level of creatinine in the blood and kidneys.
As evidenced by abnormal creatinine
Deviation of creatinine from the norm does not always occur due to the development of the disease, the fluctuations of the substance in the human body are due to various physiological factors. Athletes, ballerinas, vegetarians, representatives of professions that require vigorous physical activity, all these categories of people are subject to drastic changes in creatinine in the blood.
Deviations due to external factors are not critical and show that a person leads an active lifestyle. Muscles are often under stress, which leads to an increase in this substance. However, changes in the substance in the blood can also be caused by the development of various pathologies.
There are the following physiological factors:
- A set of muscle mass (athletes, weightlifters, bodybuilders, wrestlers);
- Consumption of large amounts of food containing high amounts of protein;
- The use of anti-inflammatory drugs (Nurofen, Ibufrofen, Spasmogon);
- Antibiotics.
Pathologies may be as follows:
- Renal failure;
- Malfunctions related to the endocrine system;
- Enlargement of the thyroid gland;
- An overabundance of hormones in the body associated with metabolic or hormonal disruption;
- Circulatory system diseases;
- Heart failure;
- Oncology;
- Muscle damage (injuries, tears);
- Diabetes.
As a result of disease progression, unpleasant consequences may occur. Possible complications:
- Partial urinary problems or full delay;
- Constant aching pain in the lower back;
- Swelling of the legs;
- Rapid breathing;
- Brief darkening of the eyes;
- Increased pressure.
The manifestation of the symptoms described above is not a reason to assert that the malaise is directly related to an increase or decrease in the level of creatinine in the body.
Only a comprehensive analysis is able to give an objective assessment of the state of the body.
How to normalize creatinine
The level of creatinine in the body can be reduced by a slight change in diet, if the cause of his elevation was not a serious disease or the development of pathology. There are some simple tips that can help normalize the level of creatinine in the blood with a slight increase. The following steps should be taken:
- Control the amount of meat that a person consumes. Weekly rate is 500 grams of meat. Three to a week to eat 150-175 grams of meat. Meat should not be fat, it is necessary to exclude pork and give preference to veal, chicken, turkey, rabbit;
- Protein is desirable to use vegetable;
- It should be included in the diet of food that has a rich supply of fiber and normalizes the bowels. The most suitable type of food that can provide all the necessary substances to the body are various cereals: buckwheat, oatmeal, millet;
- Normalize the water balance in the body. The daily rate for an adult is more than two liters of fluid. The most important intake of water is in the morning on an empty stomach;
- Creatinine level is caused by physical exertion, in order to normalize the amount of substance, it is necessary to minimize physical exertion. Stressful situations when adrenaline is released into the blood should also be tried to remove from life;
- It is necessary to be in a state of emotional rest, to control violent feelings, to prevent the emergence of conflict situations.
In the event of an increase in the level of creatinine, the examination and diagnosis of a serious disease associated with impaired renal function, it is necessary to immediately consult a doctor.
In the presence of the progression of negative processes and the development of the disease, the normalization of the amount of creatinine in the blood is caused by the need to use drugs. The use of drugs is possible only after examination and prescription of a course of treatment by a doctor. Independent attempts to increase creatinine levels can cause progression of the disease.
For what you need to investigate creatinine in the blood, you can learn more from the following video.
