For disorders of the mind and brain activity, the drug Sonapaks is often used. This tool is included in the group of antipsychotic antipsychotics. It is used in psychiatry to treat the corresponding pathologies.
But before you apply, be sure to consider the instructions and features of the use of this drug.
Release form, composition and packaging
Sonapaks is available in pill form. They have a round shape with a biconvex surface. The color of the tablets is light pink or light yellow. The main active ingredient of the drug is thioridazine, its dosage in 1 tablet is 10 and 25 mg.
In addition to the active component, there are additional elements in the composition:
- talc;
- potato or potato starch;
- magnesium stearate;
- colloidal silicon dioxide;
- stearic acid;
- sucrose;
- gelatin;
- acacia gum.
Tablets are packaged in a cellular contoured packaging of 20 pieces with a dosage of 10 mg and 30 pieces with a dosage of 25 mg. In one cardboard box placed 2 or 3 blisters with the appropriate number of tablets. Also in the box there is an instruction with a complete description of the drug.
pharmachologic effect
Sonapaks has a neuroleptic, tranquilizing, anti-depressive effect.
The main active ingredient of the tablets is thioridazine, which has a suppressive effect on adrenergic and dopamine impulse transmission at the level of the reticular formation, brainstem and its cortex.
Due to this, the active ingredient has antipsychic and mild antidepressant therapeutic effects.
After taking the drug, the active substance is quickly and completely absorbed into the systemic circulation. Metabolized in the liver, with the formation of inactive decay products, the elimination of which occurs with the help of urine. Therapeutic effect is observed not immediately after the start of treatment, but after about 10-12 days.
Indications and contraindications
Sonapax is recommended for the treatment of psychiatric disorders.
- for the treatment of schizophrenia. In these cases, the medication Sonapaks is recommended to be used as part of a combination treatment with other drugs;
- recommended for severe behavioral disorders, which are accompanied by severe aggressiveness of the person and the inability to long-time concentration of attention;
- in the presence of increased psychomotor activity of a person with a different nature of origin;
- it is used for neurotic states that are accompanied by psychomotor agitation, tension with a psycho-emotional nature, fears, anxiety, depressive disorders, and obsessive thoughts;
- in psychotic disorders that are characterized by the development of hyperreactivity and increased arousal;
- often prescribed in the presence of withdrawal symptoms. The drug is recommended to be used as part of complex therapy in the presence of physical and psychological dependence on alcohol, as well as on compounds of narcotic and toxic species.
But it is worth remembering that the drug has some contraindications. The instructions indicate a number of pathological and physiological conditions in which it is not recommended to take the drug:
- the lack of functional activity of the kidneys;
- It should not be used in the presence of reduced activity of liver enzyme CYP2D6, which provides a complete metabolism of the active element of the drug;
- arrhythmia - violation of the rhythm of heart contractions;
- during marked suppression of the functional activity of structures in the central nervous system;
- with liver failure with varying degrees of severity;
- with patient comatose conditions;
- pathological processes of the circulatory system and red bone marrow, as well as transferred in the past;
- not recommended in the presence of pronounced depressive states;
- in the presence of an extended QT interval on the electrocardiogram;
- It should not be taken together with medicines, which can lead to a prolongation of the QT interval on the electrocardiogram;
- undesirable to use in conditions in which there is a violation of the digestion and absorption of carbohydrates in the intestine;
- not recommended for children under the age of 4;
- with individual intolerance of the active element and additional substances.
Instructions for use for adults and children
The drug Sonapaks recommended to be taken orally. They should be taken as a whole, they should not be chewed, do not break when taken.
Drink plenty of water to make it easier to take.
The regimen and dosage should be appointed only by the attending physician, depending on the patient's condition and indications.
The instructions indicate different reception regimens depending on the state:
- Mild intellectual and emotional disorders. During these conditions, the average dosage of the drug ranges from 50 to 200 mg per day. Therapeutic therapy should begin with a small dose, which gradually increases until a pronounced therapeutic effect appears;
- In psychosis, treatment therapy is prescribed in a hospital. The smallest dose is 25-75 mg per day. Then the dosage is gradually increased to 250-800 mg per day; it should be increased until a pronounced therapeutic effect is achieved. After the patient has an improvement, it will be possible to switch to a maintenance dosage - 75-200 mg per day. Take the drug is recommended at night before bedtime. The course of taking the pills is 2-4 weeks;
- For psychosomatic disorders, it is recommended to take the medicine at a dose of 10-75 mg per day.
For children, the drug should be used in reduced dosages, which depend on age:
- children aged 4 to 7 years should take from 10 to 20 mg per day;
- from 7 to 14 years old - from 20 to 30 mg;
- between the ages of 15 and 18, 30–50 mg.
The use of tablets Sonapaks during pregnancy and lactation
The drug Sonapaks not recommended for use in carrying a child. However, the instructions indicate that the use of tablets is possible only in cases where the expected benefit to the mother will be higher than the possible risk to the child. But an adequate study of the safety of the drug during pregnancy was not performed.
Side effects and overdose
While taking the drug, unpleasant effects from various internal organs and systems can occur, including the following:
- problems with the heart and blood vessels - lowering blood pressure, this condition often occurs when the horizontal position of the body changes to the vertical, frequent heartbeat can also appear - the state of tachycardia;
- problems in the nervous system - often there are parkinsonism phenomena that are accompanied by a disorder of the motor functions of the nervous system, often convulsive seizures, severe irritability, drowsiness symptoms, depression, delusional thoughts can occur;
- a decrease in the level of leukocytes and granulocytes may be noted in the blood;
- violation of the digestive organs - constipation, manifestation of jaundice symptoms, which are associated with problems of normal removal of bile from the structures of the hepatobiliary system into the cavity of the duodenum;
- the occurrence of increased sensitivity of the skin to light;
- skin rash may sometimes occur, which may be accompanied by an itchy sensation;
- increase or decrease in blood glucose levels;
- menstrual disorder in women, decreased sexual desire for a partner.
When taking the drug in higher dosages, overdose symptoms may appear:
- blood pressure may drop significantly until shock occurs;
- arrhythmia;
- depression of the functional activity of the brain, signs of convulsions, a disorder of consciousness that can lead to coma;
- respiratory edema may occur, and breathing difficulties may occur;
- upset stool, intestinal obstruction;
- decreased urination
Drug interactions, special instructions
Drug Sonapaks causes increased action of painkillers, sleeping pills, narcotic drugs.
When used in conjunction with epinephrine, it causes a decrease in blood pressure.
During use with antihistamine and antidiabetic drugs, the effect of Sonapax is enhanced. Lowers the effectiveness of anti-appetite drugs, anticoagulants.
When used in conjunction with cisapride, astemizole, quinidine increases the likelihood of developing tachycardia.
When using Sonapaks together with anticonvulsant drugs, its effect is reduced.
The drug can also interact with many other drugs, so when you need to take it is necessary to consult with your doctor.
Also, when receiving it is necessary to take into account the important instructions:
- Sonapax should be prescribed only by the attending physician, he must also indicate the correct regimen;
- during the application should refrain from the use of alcoholic beverages;
- when using it is necessary to monitor the state of peripheral blood;
- during pregnancy it is used only when absolutely necessary;
- during lactation for the period of taking the medicine, it is worth refusing to breastfeed;
- elderly people are prescribed in reduced dosages.
The price of the drug, its analogues
The cost of tablets in different pharmacies may vary. On average, one pack with a dosage of 10 mg and the number of tablets 60 pieces costs 270-280 rubles. Packaging tablets number 60 with a dosage of 25 mg costs from 450 to 470 rubles.
Also in the pharmacy there are analogues of this tool:
- Tioril. Packaging number 100 with a dosage of 25 mg costs about 120-140 rubles;
- Betamax. A pack of 50 mg, 30 pieces costs 190 rubles, 100 mg, 30 pieces - 270 rubles;
- Azaleptin. Packaging No. 50 25 mg - 450 rubles, 100 mg - 1200 rubles;
- Rispolept. Packaging 20 tablets with a dosage of 2 mg - 570-580 rubles, with a dosage of 4 mg - 1130-1170 rubles.
Reviews of the drug Sonapaks
Sonapaks was prescribed to me by a doctor for the treatment of neurosis and insomnia. At first, I was scared by a large list of contraindications and side effects. But after I started taking this remedy, I immediately became much better and I did not find any unpleasant symptoms in myself. A week later, my nerves became even stronger, and I began to sleep just like a baby.
Marina, 45, Moscow
A child of 6 years on the background of emotional over-excitement had a nervous tic - he began to squint his eyes severely. I thought it was due to vision problems and decided to go to an optometrist, but the doctor referred us to a neurologist. After the examination, we were prescribed to take Sonapaks, but in reduced dosages. Surprisingly, after 8 days I noticed improvements, and a week later all the unpleasant symptoms disappeared.
Christina, 37 years old, Omsk
Additional information about Sonapaks can be found in the following video.
