Suffering from pain of unknown etiology, epilepsy attacks are unbearable, they torment the body and soul. In search of a cure, patients are ready for anything. Comes to the aid of pharmacology, offering a drug called Lyrics.
The composition of the capsules of the drug
WHO recommended exclusive name of the drug substance is Pregabalin. In 1 capsule (different dosages) are the following components:
- active: pregabalin (different dosages) - an analogue of gamma-aminobutyric acid;
- auxiliary: lactose monohydrate - milk sugar, sweetener;
- corn starch - filler;
- talc - provides tight contact of particles;
- constituent elements of the hard shell of the encapsulate: iron oxide - red dye; titanium dioxide - titanium white; gelatin is a collagen hydrolyzate that forms the body of the capsule.
As can be seen from the characteristics, all elements of the drug are safe and licensed. A valuable product is created by the company Pfizer, location - Germany. Release form: the dosed medicine consisting of a hard gelatin shell with an encapsulant, the dosage size is marked with color.
Pharmacological action and indications for use
The tool has antiepileptic effect due to the binding of neurons with calcium channel subunits and is indicated for use:
- with neuropathic pain - to reduce pain;
- with fibromyalgia - to reduce pain, muscle spasms, restore sleep;
- with epileptic and partial paroxysms - to reduce the frequency of seizures;
- in various states of anxiety, nervous system disorders, panic attacks - to eliminate symptoms.
The drug is taken orally, excreted through the kidneys after 6 hours.
Patients with dysfunction of the organs of excretion must change the dosage of the drug:
- in case of impaired filtration and secretion in the kidneys, it is recommended to reduce the amount of the drug;
- while on hemodialysis, on the contrary, increase;
- when changing the functions of the liver, leave the dosage unchanged;
- Older people are recommended to reduce the dose.
This video contains information about taking the drug and its effects.
Instructions for use of the drug Lyrics
The medication is ingested by swallowing, both during meals and on an empty stomach.
| History for use | Drug dosage |
|---|---|
| Neuropathic pain | Beginning of the course - twice 75 mg (150 mg / day) (Efficacy and tolerability checked) After 3-7 days, the dose is doubled (300 mg / day). If necessary, increase the dose in a week: maximum - 600mg / day. |
| Epileptic and partial paroxysms | According to the above scheme
|
| Diffuse musculoskeletal pain | According to the above scheme, after two weeks the dosage is no more than 450 mg / day., Then according to the scheme
|
| Nervous system disorders, anxiety, panic attacks | According to the above scheme, after two weeks the dosage is no more than 450 mg / day., Then according to the scheme |
Rules for accepting Lyrics:
- drug withdrawal should be gradual, as the patient develops addiction;
- in patients with changes in renal filtration and secretion, the dose is calculated on the basis of the estimated creatinine clearance ml / min;
- You can not practice the simultaneous reception of two doses.
Contraindications, side effects, precautions
The drug is contraindicated for use:
- children from 0 to 17 years old (inclusive);
- with hereditary diseases;
- with allergic reactions.
Side effects are marked as very frequent (1 case per 10), frequent (1 case per 100), infrequent (1 case per 1000) and rare (1 case per 1500).
| System organ class | Unwanted reaction | Frequency of occurrences (cases) |
|---|---|---|
| Infections | Nasopharyngitis | 1 per 100 |
| Blood and lymphatic system | Decreased neutrophil level | 1 per 1000 |
| Metabolic disease | Bouts of gluttony | 1 per 100 |
| Refusal of food | 1 per 1000 | |
| Nervous disorders | From euphoria to panic Hallucination and depersonalization, Speech difficulties, anorgasmia Inhibition | 1 per 100 1 per 1000 1 per 1000 1 to 1500 |
| Neuralgia | Dizziness, drowsiness, headaches | 1 in 10 |
| Motion misalignment in different muscle groups | 1 per 100 | |
| Fainting to the point of loss of consciousness | 1 per 1000 | |
| Falling into a stupor | 1 to 1500 | |
| Visual system | Blurred Outlines | 1 per 100 |
| Eye inflammation, decreased visual acuity | 1 to 1500 | |
| Strabismus, loss of vision, fluctuation of visible objects | 1 to 1500 | |
| The cardiovascular system | Heartbeat rhythm change | 1 per 1000 |
| Respiratory system | Dyspnea with cough Lung paste | 1 per 1000 1 to 1500 |
| Organs of hearing | Vertigo | 1 per 100 |
| Epithelial system | Candidiasis, urticaria, rash. | 1 per 1000
|
| Musculoskeletal system | Painful cramps Diffuse musculoskeletal pain Rabdomiliosis | 1 per 100 1 per 1000 1 to 1500 |
| urinary system | Incontinence | 1 per 1000
|
| Reproductive system | Breast engorgement, temporary impotence Excretion of milk from the breast. | 1 per 100 1 to 1500 |
| General changes | Gait disturbance with frequent falls, Pastoznost, chills | 1 per 100 1 per 1000 |
| Lab tests | Quick weight gain Slimming, high blood sugar Decrease in the number of white blood cells | 1 per 100 1 per 1000 1 to 1500 |
| Immunity system | Allergic reactions Anaphylactic shock | 1 to 1500 1 to 1500 |
Similar drugs
The price range of Lyrics - from 650 to 2510 rubles per pack, depends on the dosage of the drug and the number of capsules. The drug is sold only by prescription.
There are no analogs (preparations containing different active substances, but with a similar effect) Lyrics caps.
Drug-synonyms (containing the same active ingredients) capsules Lyrics: Pregabalin Richter, Algerika, Prabegin, Pregabalin, Pregabalin Zentiva, Pregabalin canon, Pregabalin-SZ, Pregabilon, Replica.
The mechanism of action of the drug can be studied in a small video.
Reviews
The reviews are mostly positive, patients are frightened only by the addiction syndrome and the limitation of driving.
Alla, 58 years old
Veniamin, 43 years old
